diff --git a/src/core/cff_parser.js b/src/core/cff_parser.js
index 2a8935dd8..ee78174da 100644
--- a/src/core/cff_parser.js
+++ b/src/core/cff_parser.js
@@ -17,6 +17,7 @@ import {
   bytesToString,
   FormatError,
   info,
+  isArrayEqual,
   shadow,
   stringToBytes,
   Util,
@@ -33,6 +34,20 @@ import { DataBuilder } from "./data_builder.js";
 // Maximum subroutine call depth of type 2 charstrings. Matches OTS.
 const MAX_SUBR_NESTING = 10;
 
+function looksLikeUnsigned16BitNegative(coord) {
+  return coord > 0x7fff && coord <= 0xffff;
+}
+
+function recoverSigned16BitBBox(bbox, onlyLowerLeft = false) {
+  return Util.normalizeRect(
+    bbox.map((coord, i) =>
+      (!onlyLowerLeft || i < 2) && looksLikeUnsigned16BitNegative(coord)
+        ? coord - 0x10000
+        : coord
+    )
+  );
+}
+
 /**
  * The CFF class takes a Type1 file and wrap it into a
  * 'Compact Font Format' which itself embed Type2 charstrings.
@@ -268,13 +283,36 @@ class CFFParser {
     }
 
     let fontBBox = topDict.getByName("FontBBox");
-    if (fontBBox?.every(coord => coord === 0) && properties.bbox) {
-      fontBBox = Util.normalizeRect(
-        properties.bbox.map(coord =>
-          coord > 0x7fff && coord <= 0xffff ? coord - 0x10000 : coord
-        )
-      );
+    const descriptorBBox = properties.bbox?.some(coord => coord !== 0)
+      ? recoverSigned16BitBBox(properties.bbox)
+      : null;
+    const cffBBoxHasUnsignedLowerLeft = fontBBox
+      ?.slice(0, 2)
+      .some(looksLikeUnsigned16BitNegative);
+    const cffBBoxHasUnsignedCoords = fontBBox?.some(
+      looksLikeUnsigned16BitNegative
+    );
+    if (fontBBox?.every(coord => coord === 0) && descriptorBBox) {
+      // The CFF FontBBox is empty, hence fall back to the FontDescriptor bbox.
+      fontBBox = descriptorBBox;
       topDict.setByName("FontBBox", fontBBox);
+    } else if (cffBBoxHasUnsignedCoords) {
+      const recoveredFontBBox = recoverSigned16BitBBox(fontBBox);
+      const descriptorCorroborates =
+        descriptorBBox &&
+        properties.bbox.some(coord => coord < 0) &&
+        !properties.bbox.some(looksLikeUnsigned16BitNegative) &&
+        isArrayEqual(recoveredFontBBox, descriptorBBox);
+
+      if (descriptorCorroborates || cffBBoxHasUnsignedLowerLeft) {
+        // Some Ghostscript-generated CFF fonts encode negative lower-left
+        // coordinates as unsigned 16-bit values. Preserve large upper-right
+        // coordinates unless the descriptor independently confirms the repair.
+        fontBBox = descriptorCorroborates
+          ? recoveredFontBBox
+          : recoverSigned16BitBBox(fontBBox, /* onlyLowerLeft = */ true);
+        topDict.setByName("FontBBox", fontBBox);
+      }
     }
     if (fontBBox?.some(coord => coord !== 0)) {
       // adjusting ascent/descent
diff --git a/test/pdfs/.gitignore b/test/pdfs/.gitignore
index 16ebf27c2..e866a0f1f 100644
--- a/test/pdfs/.gitignore
+++ b/test/pdfs/.gitignore
@@ -923,3 +923,4 @@
 !issue18032.pdf
 !Embedded_font.pdf
 !issue18548_reduced.pdf
+!issue_cff_unsigned_bbox.pdf
diff --git a/test/pdfs/issue_cff_unsigned_bbox.pdf b/test/pdfs/issue_cff_unsigned_bbox.pdf
new file mode 100644
index 000000000..c31688d7c
Binary files /dev/null and b/test/pdfs/issue_cff_unsigned_bbox.pdf differ
diff --git a/test/test_manifest.json b/test/test_manifest.json
index 9c9153bdc..6b6ba745f 100644
--- a/test/test_manifest.json
+++ b/test/test_manifest.json
@@ -14320,5 +14320,12 @@
     "firstPage": 1,
     "lastPage": 1,
     "type": "eq"
+  },
+  {
+    "id": "issue_cff_unsigned_bbox",
+    "file": "pdfs/issue_cff_unsigned_bbox.pdf",
+    "md5": "d2606e2c6cc9e679b8b88c2800c6e1a9",
+    "rounds": 1,
+    "type": "eq"
   }
 ]
diff --git a/test/unit/cff_parser_spec.js b/test/unit/cff_parser_spec.js
index e5ddd905b..dc9555846 100644
--- a/test/unit/cff_parser_spec.js
+++ b/test/unit/cff_parser_spec.js
@@ -154,6 +154,90 @@ describe("CFFParser", function () {
     expect(properties.ascentScaled).toEqual(true);
   });
 
+  it("repairs a FontBBox with unsigned-encoded negative coordinates", function () {
+    // [-456, -305, 2158, 989] encoded as unsigned 16-bit values; produced
+    // by some Ghostscript-generated CFF fonts.
+    cff.topDict.setByName("FontBBox", [65080, 65231, 2158, 989]);
+    const fontDataRepaired = new CFFCompiler(cff).compile();
+
+    const properties = {
+      bbox: [-456, -305, 2158, 989],
+    };
+    const reparsedCff = new CFFParser(
+      new Stream(fontDataRepaired),
+      properties,
+      SEAC_ANALYSIS_ENABLED
+    ).parse();
+
+    expect(reparsedCff.topDict.getByName("FontBBox")).toEqual([
+      -456, -305, 2158, 989,
+    ]);
+    expect(properties.ascent).toEqual(989);
+    expect(properties.descent).toEqual(-305);
+    expect(properties.ascentScaled).toEqual(true);
+  });
+
+  it("doesn't replace a repairable FontBBox with an empty descriptor bbox", function () {
+    cff.topDict.setByName("FontBBox", [65080, 65231, 2158, 989]);
+    const fontDataRepaired = new CFFCompiler(cff).compile();
+
+    const properties = {
+      bbox: [0, 0, 0, 0],
+    };
+    const reparsedCff = new CFFParser(
+      new Stream(fontDataRepaired),
+      properties,
+      SEAC_ANALYSIS_ENABLED
+    ).parse();
+
+    expect(reparsedCff.topDict.getByName("FontBBox")).toEqual([
+      -456, -305, 2158, 989,
+    ]);
+    expect(properties.ascent).toEqual(989);
+    expect(properties.descent).toEqual(-305);
+    expect(properties.ascentScaled).toEqual(true);
+  });
+
+  it("repairs unsigned-encoded negative FontBBox without descriptor data", function () {
+    cff.topDict.setByName("FontBBox", [65080, 65231, 2158, 989]);
+    const fontDataRepaired = new CFFCompiler(cff).compile();
+
+    const properties = {};
+    const reparsedCff = new CFFParser(
+      new Stream(fontDataRepaired),
+      properties,
+      SEAC_ANALYSIS_ENABLED
+    ).parse();
+
+    expect(reparsedCff.topDict.getByName("FontBBox")).toEqual([
+      -456, -305, 2158, 989,
+    ]);
+    expect(properties.ascent).toEqual(989);
+    expect(properties.descent).toEqual(-305);
+    expect(properties.ascentScaled).toEqual(true);
+  });
+
+  it("preserves large positive upper FontBBox coordinates", function () {
+    cff.topDict.setByName("FontBBox", [0, -305, 40000, 989]);
+    const fontDataRepaired = new CFFCompiler(cff).compile();
+
+    const properties = {
+      bbox: [0, -305, 40000, 989],
+    };
+    const reparsedCff = new CFFParser(
+      new Stream(fontDataRepaired),
+      properties,
+      SEAC_ANALYSIS_ENABLED
+    ).parse();
+
+    expect(reparsedCff.topDict.getByName("FontBBox")).toEqual([
+      0, -305, 40000, 989,
+    ]);
+    expect(properties.ascent).toEqual(989);
+    expect(properties.descent).toEqual(-305);
+    expect(properties.ascentScaled).toEqual(true);
+  });
+
   it("repairs likely Ghostscript-zeroed FDArray private defaults", function () {
     cff.isCIDFont = true;
     cff.topDict.setByName("ROS", [0, 0, 0]);